The General Introduction of Standard Animal CRISPR Libraries
Animal genetic screening is useful for studying molecular mechanisms that influence growth, reproduction, disease resistance, meat quality, and other key traits. Additionally, genetic screening enhances prevention and treatment strategies for viral infection. The CRISPR gene screening system provides a large-scale, multi-dimensional tool for molecular breeding.
Synbio Technologies uses the genetic blueprints of sheep, rabbits, pigs, dogs, and cattle to develop its CRISPR knockout libraries. These libraries come in single- or dual-vector systems with puro selectable markers and can be packaged with lentiviruses for efficient cell transfection and screening. By providing
CRISPR libraries for species beyond
humans and
mice, our animal CRISPR knockout libraries address a market gap and enhance the use of CRISPR in molecular breeding, regenerative medicine, and research on animal models of human diseases.
Highlights
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- High Target Activity and Low Off-target Rate sgRNA Sequences
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- Easy Cell Delivery and Screening Achieved
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- High Edit-efficient CRISPR Libraries
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- >99.9% Library Coverage, >80% Accuracy, and <10 Uniformity
Service Details
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Catalog
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Product Name
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Sequence Information
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Amount
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Price
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STCRI100088
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Syno Sheep Genome CRISPR Knockout Libraries
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20,400 targeted genes, 118,626 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.
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200 μg
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Quote
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STCRI100100
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Syno Rabbit Genome CRISPR Knockout Libraries
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19,669 targeted genes, 77,192 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.
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200 μg
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Quote
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STCRI100137
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Syno Dog Genome CRISPR Knockout Libraries
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19,523 targeted genes, 77,440 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed. 40,779 sgRNA sequences targeted lncRNA
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200 μg
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Quote
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STCRI100115
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Syno Pig Genome CRISPR Knockout Libraries
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20,823 targeted genes, 119,719 sgRNA sequences and 1,000 control (non-targeted) sgRNA sequences designed.
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200 μg
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Quote
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STCRI100124
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Syno Cattle Genome CRISPR Knockout Libraries
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21,698 targeted genes, 130,015 sgRNA sequences and 2,000 control (non-targeted) sgRNA sequences designed.
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200 μg
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Quote
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Workflow
FAQs
Synbio Technologies’ sgRNA designs are not limited to species, other animal libraries can be customized upon request.
Animal genome-wide knockout libraries can be used for various applications, including:
Breeding for Disease Resistance: These libraries allow for screening host factors linked to viral infections, such as PDCoV and ASFV, to identify new targets for developing antiviral genetically modified animals.
Disease Research: They help in understanding the mechanisms of viral infections by identifying host factors involved, leading to the discovery of effective preventive and control measures.
It is recommended to store animal genome-wide libraries at -20℃
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