The General Introduction of Antibody Affinity Maturation
The binding affinity of an antibody is one of the key parameters to determine the efficacy and dosage of an antibody drug. The main methods for improving the binding affinity of antibodies focus on site mutation, CDR rearrangement, and DNA recombinant. Our unique and effective affinity maturation technology allows us to quickly spot the key amino acid site in an antibody domain, which increases the binding affinity of the
antibody, reaching at least nM level.
Highlights
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- Effective Random Mutation through DNA Shuffling
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- Mature Phage Display Platform Assuring High-Quality Affinity Maturation Services
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- Precise Affinity Evaluation
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- Competitive Price
Service Details
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Details
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Deliverables
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Turnaround Time
(Business Days)
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DNA Shuffling
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1. Antibody sequence and sequencing report
2. Top 1-3 of the optimized antibodies
3. Full analysis report (PDF)
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6-7 Months
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Library Construction and Screening
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Antibody Production and Characterization
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Workflow
Resources
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