The General Introduction of Peptide Library
Peptide libraries are widely used in life science research fields, such as drug discovery, vaccine development, proteomics, and immunotherapy.
Synbio Technologies has a rapid high-throughput parallel
peptide synthesis platform that provides large-scale peptide synthesis at a low cost. We offer a flexible selection of peptide purity levels ranging from crude to 99% purity. All purified peptides are delivered with QC reports of HPLC, MS, and COA to ensure the highest quality.
Highlights
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- High Throughput
> 8,000 peptides each month
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- Fast Turnaround Time
Delivery within 2-3 weeks, 1-2 weeks if urgent
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- High Quality Products
Complete HPLC, MS, and COA reports
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- Customizable Purity Level
Peptide purity levels range from crude to 99%
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- Various Peptide Libraries
Protein libraries to meet customer different needs
Service Details
Types of Peptide Library
• Truncation Peptide LibraryView More
These determine the minimal epitope by gradually removing amino acids from both ends of a peptide sequence, identifying the minimal sequence associated with the activity.
• Random Peptide LibraryView More
20 natural amino acids randomly replace specific residues, creating diverse peptide sequences. This is widely used in peptide screening to discover new active peptides or target regions.
• Positional Scanning LibraryView More
Specific positions within a peptide sequence are systematically replaced by other amino acids to optimize the sequence. The amino acids best suited for specific positions are identified.
• Alanine Scanning LibraryView More
Each amino acid in a peptide is sequentially replaced by alanine to assess its impact on the overall peptide structure, function, and biological activity. This aids in identifying key amino acids.
• Scrambled LibraryView More
Internal amino acid substitutions in an original peptide sequence serve as negative controls to confirm critical sequences. This library is widely used in targeted molecular probe screening and discovering new protein functions.
• Overlapping Peptide LibraryView More
By progressively truncating from the N-terminus to the C-terminus of a protein, epitopes associated with specific biological activities are able to be discovered. Furthermore, the screening of these linear or contiguous epitopes allows for peptides to be designed.
Purity: crude, desalted, translated, >70%, >75%, >80%, >85%, >90%, >95%, >98%, >99%.
Synthesis length: 1-30 AA。
Turnaround Time:2-3 weeks, fastest 1-2 weeks.
Deliverables
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Peptide Products
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HPLC QC Reports
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MS QC Reports
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Certificate of Analysis Documents
FAQs
When using peptide libraries for screening, it is important to take into account the experimental design, the purity and concentration of the peptide, and the optimization of the screening conditions, and the accuracy of the data analysis.
Peptide modifications can improve the physicochemical properties of peptides, such as increasing water solubility, improving stability, enhancing biological activity, and prolonging in vivo action time. Common modifications include C-terminal, N-terminal, intermediate residues,and cyclisation modifications.
Peptide libraries have a variety of applications, such as drug discovery, epitope mapping, protein-protein interaction studies, enzyme substrate identification, and receptor-ligand binding assays.
Resources
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