DNA synthesis is a method in synthetic biology for the creation of deoxyribonucleic acid biopolymers in a sequence-specific manner. DNA synthesis can be further classified into oligonucleotide synthesis and gene synthesis. Currently, oligonucleotides are manufactured almost exclusively using automated solid-phase methods.In this way, we can apply efficient and accurate DNA synthesis services. Oligonucleotide synthesis produces short, single-stranded nucleic acid polymers usually made up of 18 to 25 nucleotides, which are usually used as probes for detecting specific DNA/RNA sequences by recognizing and binding to a complementary segment of DNA/RNA. Oligonucleotides are widely used as DNA/RNA structure probes, DNA microarray probes, and gel electrophoresis references, and are usually single strand fragments limited to 100 nucleotides. On the other hand, gene synthesis is able to create double-stranded DNA ranging from 50 bp to 12,000 bp in length. Solid-phase based gene synthesis opens up new avenues for completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size.

Synbio Technologies’ DNA Synthesis Service

Taking advantage of industrial-leading processing technology, Synbio Technologies’ Syno 1.0 platform provides a full selection of conventional primers, ultra-high purity primers, degenerate primers, aptamers, and fluorescent probes for world-class scientific research and some industrial customers. Synbio Technologies can also manufacture large scale primer synthesis using multi-well plates to deliver up to 10,000 primers for customized orders.

Our Syno 2.0 DNA synthesis platform is the most versatile platform empowered by patented Syno DNA Assembly technologies. Syno 2.0 platform can cope with any type of gene and genome ranging from 100 base pairs to 1 million base pairs that contain all types of complex sequences. Standard complexity order can be completed within 5 business days with 100% sequence fidelity. NG Codon optimization software is developed at Synbio Technologies to boost the expression of synthetic genes in all commonly used expression systems.